Our Process

Con­ven­tion­al chem­i­cal syn­the­ses fail at com­plet­ing pep­tides with extreme prop­er­ties cor­rect­ly. Some pep­tides crum­ble or repel their amino acid build­ing blocks dur­ing the con­struc­tion of the amino acid chain.

Biosyn­the­sis over­comes these prob­lems and allows for the pro­duc­tion of com­plex pep­tides. The mk2 Biotech­nolo­gies process is designed to cir­cum­vent purifi­ca­tion trou­bles that occur in both state of the art chem­i­cal and bio­log­i­cal syn­the­ses. It is based on the well-known recom­bi­nant syn­the­sis route suc­cess­ful­ly applied for pro­duc­tion of long-chained pro­teins, though includes sev­er­al ground­break­ing improve­ments mak­ing the tech­nol­o­gy ful­ly applic­a­ble to short and medi­um length pep­tide classes.

Customer Promises

  • Super Puri­ty: Our process allows the pro­duc­tion of pep­tides with puri­ties >99% which can be fur­ther increased for indi­vid­ual needs. It is not nec­es­sary for the cus­tomer to pro­vide inhouse purifi­ca­tion know-how and infrastructure.

  • Arbi­trary Sequences and Prop­er­ties: The syn­the­sis of any amino acid sequence is our pecu­liar strength. We can pro­vide pep­tides with any charge, polar­i­ty, hydropho­bic­i­ty etc.

  • Ecofriend­ly: The syn­the­sis of pep­tides by mk2 Biotech­nolo­gies is high­ly envi­ronem­n­tal friend­ly since no tox­ic waste is pro­duced and most of the bio­log­i­cal side prod­ucts are ful­ly recyclable.

  • Flex­i­ble Chain Length: mk2 Biotech­nolo­gies can pro­vide indi­vid­u­al­ly designed pep­tides includ­ing inter­me­di­ate chain lengths of 25-100 amino acids.

  • Scal­a­bil­i­ty: Our process is high­ly scal­able and automat­able. We there­fore can sup­ply pep­tides for big­ger sized appli­ca­tions at con­stant high quality.

  • Func­tion­al­iza­tion: The process offers the pos­si­bil­i­ty to func­tion­al­ize our prod­ucts with sev­er­al kinds of bio­log­i­cal or chem­i­cal func­tion­al groups like pho­to­lu­mi­nes­cent mark­ers, click­able groups and others.

Social Impact

In the lat­est 50 years the world­wide tech­nol­o­gy went through an orig­i­nal­ly unimag­in­able devel­op­ment. Though, the major tech­no­log­i­cal improve­ments were achieved in the field of IT and dig­i­tal­iza­tion, while oth­er fields of tech­nol­o­gy slow­ly pas­si­vat­ed. While the social chal­lenges aris­ing from the grow­ing world pop­u­la­tion and the simul­ta­ne­ous demand of wealth and pros­per­i­ty in every sin­gle cor­ner of our world, the stag­nat­ing tech­nol­o­gy fields were unable to find new and more effec­tive solu­tions. There­fore, many actu­al chal­lenges are faced by the “more-approach”. More surg­eries, more med­ica­tions, more fer­til­iz­ers; the list appears to be infi­nite. Unfor­tu­nate­ly, this approach does not sim­ply get to grips with the symp­toms, but at the same time wors­ens their ori­gin: Ecosys­tems and every sin­gle part of it become more and more sen­si­tive to any exter­nal influ­ence and loose more and more their nat­ur­al buffer capa­bil­i­ties. This results into an expo­nen­tial demand of state-of the-art solu­tions lead­ing into a vicious cir­cle. Our mod­ern tech­nolo­gies in many cas­es actu­al­ly do not pro­vide solu­tions any­more, they rather relo­cate the crit­i­cal point of break­down to future times.

We at mk2 Biotech­nolo­gies are strong­ly con­vinced, that our nov­el pep­tide syn­the­sis tech­nol­o­gy has the poten­tial to tack­le parts of the major social chal­lenges and pro­vide solu­tions for a known and yet unknown demand for chem­i­cal and/or bio­log­i­cal active sub­stances. We believe to con­tribute sig­nif­i­cant­ly e.g. in the reduc­tion of the “agri­cul­tur­al chemother­a­py” with tar­get-ori­ent­ed crop pro­tec­tion and the pre­ven­tion of antibi­ot­ic resis­tances in a broad field of appli­ca­tions. We fur­ther­more will pro­vide a back­bone for mod­ern med­i­cine in its bat­tle against wide­spread dis­eases by pro­vid­ing nov­el active ingredients.